The consumption of AAS and testosterone above the normal need causes hormonal disturbances.
In men, the adverse effects appear as reduced hormone production, causing, for example, structural shrinking of testicles. The extracorporeal hormone suppresses the body's own hormone production.
In female users, testosterone and anabolic steroids cause excessive growth of body hair, lowering of the voice, decreased breast size, balding, enlargement of the clitoris, skin problems and menstrual cycle disturbances.
In adolescents, growth may stop, leading to short stature.
According to a Finnish population-based study, the risk of AAS and testosterone abusers dying prematurely was 4.6 times higher than in the control group.
Oversized doses of anabolic steroids and testosterone will greatly distort body fat values. The continuous use of these hormones will increase the risk of developing heart and vascular diseases, and the risk of infarctus cordis and apoplexy. Steroids weaken the cardiac contractile force and cause cardiac muscle degeneration that increases the risk of cardiac arrhythmia and sudden death.
Abuse of AAS and testosterone increases the risk of developing diabetes. The sharing of syringes with other users increases the possibility of getting blood-transmitted diseases such as hepatitis and HIV. Overuse also increases the risk of cancer and liver damage.
Anabolic steroids and testosterone affect the central nervous system, including brain neurotransmitters and structure. During the using period, 20 to 30 percent of the people who use oversized doses have mood disorders, such as depression, anxiety, aggressiveness, and psychotic reactions with hallucinations. In addition, about 30% of anabolic steroid users experience dependence on AAS.